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Wednesday, 30 May 2012

Australian researchers develop gene modulation to treat a disorder that occurs in human genes such as hemophilia and thalassemia.

Modulation of these genes using technology Recombinant DNA Technology. The technology works by cutting off, then put the DNA and move genes between organisms.


"This is being developed and is still experimental. We use a combination of gene technology," says Professor Merlin Crossley who also served as Dean of the Faculty of Science University of New South Wales in Australia Embassy Office, Brass, Jakarta, Wednesday, May 30, 2012.


 
Crossley said, he developed a scheme of repair gene mutations by modulating genes that have mutated. Moreover, it also raised the genes from the outside through a DNA-Binding Proteins that are integrated with the genes contained in the body.


With the scheme, he argues, the gene structure is not balanced will be filled again with the delivery of genes from the outside.Gene modulation step is an attempt to get the normal gene. Human disease gene abnormalities occur, due to gene mutations that cause genes in the human body become unbalanced.


In normal circumstances, the genes provide the code and remove the protein to generate activity that goes well. Under normal conditions it makes the cells work, divide and then grow back. Under normal circumstances, there is a gene which controls.


However, the human condition have mutations in genes, gene imbalance occurs and the body needs a supply of DNA protein from the outside.


Crossley added that he does still intensive experiments in animals which developed a mouse. "Still in the animal, not to humans," he said.


He claimed to have applied it to human trials, but instead there is a problem. For hemophilia patients, he said, went well. However, for patients with leukemia after the gene mutation is even growing disease.


However, Crossley optimistic everything is going well in the future. At least, alternative solutions are developed it will be cheaper compared to other medical treatments. (Asp)

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